What are Quaaludes?
Quaaludes (methaqualone) is a synthetic, barbiturate-like, central nervous system depressant. Methaqualone is an anxiolytic and a sedative-hypnotic drug. These medicines were introduced as a safe barbiturate substitute, but they later showed that the possibility of addiction and withdrawal symptoms were similar to those of barbiturates.
Generic name: methaqualone
Common brand names: Quaalude, Sopor
Other formal names: Cateudil, Dormutil, Hyminal, Isonox, Melsed, Melsedin, Mequelone, Mequin, Methadorm, Mozambin, Optimil, Parest, Renoval, Somnific, Toquilone Compositum, Triador, Tuazole.
Common or street names: Bandits, Beirut’s, Blog Bulle, Disco Biscuits, Ewings, Flamingos, Flowers, Genuines, Lemmon 714, Lemons, Lennons, Lovers, Ludes, Mandies, Qua, Quaaludes, Quack, Quad, Randy Mandies, 714, Soaper, Sopes, Sports, Vitamin Q, Wagon Wheels
History of Quaaludes
Quaaludes were first synthesized in India in the 1950s. It was introduced into America in the 1960s and by the late 1960’s it became a popular recreational drug. The abuse potential of Quaaludes soon became apparent and in 1973 methaqualone was placed in Schedule II, making it difficult to prescribe and illegal to possess without a prescription. In 1984 it was moved to Federal Schedule I, so Quaaludes are no longer legally available in the United States.
Quaaludes that are sold for recreational use now are synthesized in illegal laboratories. Illegally produced Quaaludes can contain other central nervous system depressants such as benzodiazepines.
In the 1960s a methaqualone and diphenhydramine combination pill called Mandrax was sold as a sedative. Current Mandrax pills, made illegally, may also contain benzodiazepines, barbiturates, ephedrine, etc. Mandrax is still widely abused in South Africa.
In prescribed doses, Quaaludes promotes relaxation, sleepiness, and sometimes a feeling of euphoria. It causes a drop in blood pressure and slows the pulse rate. These properties are the reason why it was initially thought to be a useful sedative and anxiolytic.
In 1972, Quaaludes were one of the most prescribed sedatives in the United States.
It became a recreational drug due to its euphoric effect. Quaaludes were a popular drug of abuse during much of the 1970s, even though both the United States and Britain tightened control around their use and dispensing. “Luding out” where Quaaludes were taken with wine, became a popular college pastime.
When it was a legal medicine, methaqualone was available in tablet and capsule form and came in different strengths.
Oral Quaaludes dosages were 75-150 mg for light sedation. A commonly prescribed dose was 300mg. Up to 600 mg was used for strong sedation. Tolerance develops rapidly and some users may take up to 2000 mg daily to achieve the same effects.
The onset of action is approximately 30 minutes after taking this medicine and the duration of action is between 5 to 8 hours.
Overdose of Quaaludes can lead to seizures, coma, or death.
Taking doses of over 300 mg can be dangerous for first-time users. Depending on the state of the user’s tolerance, doses of about 8,000 mg per day can be fatal and others on even higher doses (of up to 20,000mg) may survive.
Death can result at much lower doses if Quaaludes is taken with alcohol, which is also a central nervous system depressant.
Quaaludes use during Pregnancy and Breastfeeding
Quaaludes are not recommended during pregnancy as the effects on human fetal development are not clear.
There is no data available about the effects of Quaaludes in breastfeeding.
Quaaludes should not be taken with alcohol or with other central nervous system depressants. This increases the depressant effects and depending on the doses taken it can be fatal.
Do not drive or operate machinery while taking this medicine.
Quaaludes Side Effects
Common side effects of Quaaludes include dizziness, nausea, vomiting, diarrhea, abdominal cramps, fatigue, itching, rashes, sweating, dry mouth, tingling sensation in arms and legs, seizures, and its depressant effects include reduced heart rate and respiration.
It can also cause erectile dysfunction and difficulty achieving orgasms. At high doses, it can cause mental confusion and loss of muscle control (ataxia).
This is not a complete list of side effects and others may occur.
Abuse and Dependence
Abuse of Quaaludes creates a barbiturate-type dependence. It is highly addictive and frequent users build a tolerance to it. It can cause withdrawal symptoms similar to barbiturates, including restlessness, irritability, nausea, vomiting, weakness, headache, insomnia, tremors, mental confusion, seizures, etc.
When it was used legally, it was found that Quaaludes users were affected negatively or dying more because of the accidents they were in, due to poor decisions made while under its influence. The driving skills of Quaalude users are impaired and also can cause fatal accidents.
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The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective, or appropriate for any given patient. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or also adverse effects.
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