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Oxycodone can be addictive. Take oxycodone exactly as directed. Do not overdo it, do not take it more often, or take it in a different way than your doctor told you to. While taking oxycodone, talk with your health care provider about your pain management goals, treatment duration, and other ways to manage your pain. Tell your doctor if you or someone in your family drinks or has drunk large amounts of alcohol, uses or has ever used illicit drugs, or has abused prescription medications, or has or has had depression or other mental illness . There is a greater risk that you will abuse oxycodone if you have or have had any of these conditions. Talk to your health care provider immediately and ask for advice if you think you have an opioid addiction, or call the US National Mental Health and Substance Abuse Administration’s (National Helpline) Helpline (SAMHSA, for your English acronym) at 1-800-662-HELP.
Oxycodone can cause serious or life-threatening breathing problems, especially during the first 24 to 72 hours of your treatment and any time your dose is increased. Your doctor will monitor you closely during treatment. Tell your doctor if you have or have ever had slow breathing or asthma. Your doctor will probably tell you not to take oxycodone. Also tell your doctor if you have or have ever had lung disease such as chronic obstructive pulmonary disease (COPD), a head injury, or any condition that increases the number of lung and respiratory diseases. pressure in your brain. The risk that you develop respiratory problems may be greater if you are an older adult or if you are weak or malnourished due to illness. If you experience any of the following symptoms, call your doctor immediately or seek emergency medical treatment: slow breathing, long pauses between breaths, or difficulty breathing.
Taking some other medicines with oxycodone may increase the risk of serious or life-threatening breathing problems, sedation or coma. Tell your doctor and pharmacist if you are taking or plan to take any of the following medications: certain antibiotics such as clarithromycin (Biaxin, in PrevPac) and erythromycin (Ery Tab, Erythrocin); certain antifungal medications including itraconazole (Onmel, Sporanox), ketoconazole (Nizoral) and voriconazole (Vfend); benzodiazepines such as alprazolam (Xanax); chlordiazepoxide (Librium); clonazepam (Klonopin); diazepam (Diastat, Valium); estazolam; flurazepam; lorazepam (Ativan); oxazepam; temazepam (Restoril); and triazolam (Halcion); carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril); medications for mental illness, nausea or pain; muscle relaxants; certain medications for the human immunodeficiency virus (HIV), including indinavir (Crixivan); nelfinavir (Viracept); and ritonavir (Norvir, in Kaletra); phenytoin (Dilantin, Phenytek); rifabutin (Mycobutin); rifampicin (Rifadin, Rimactane, in Rifamate); sedatives; sleeping pills; or tranquilizers. Your doctor may need to change the doses of your medication and monitor it carefully. If you take oxycodone with any of these medications and develop any of the following symptoms, call your doctor immediately or seek emergency medical attention: unusual dizziness, lightheadedness, extreme drowsiness, difficult or slow breathing, or unable to respond. Make sure your caregiver or family members know what symptoms may be serious so they can call the doctor or emergency medical care if you can not seek treatment on your own.
Drinking alcohol, taking medications with or without a prescription containing alcohol or using illicit drugs during your treatment with oxycodone increases the risk of you experiencing serious side effects that put your life at risk. Do not drink alcohol or take prescription or over-the-counter medications that contain alcohol or use illicit drugs during your treatment.
If you are taking oxycodone extended-release tablets, swallow them whole; do not chew, break, divide, crush or dissolve. Do not pre-wet, suck or otherwise wet the tablet before putting it in your mouth. Swallow each tablet immediately after putting it in your mouth. If you swallow broken, chewed, crushed or dissolved prolonged-release tablets, you may receive too much oxycodone at a time, instead of slowly over the course of 12 hours. This can cause serious problems, including an overdose and death.
For what conditions or diseases is this medication prescribed?
Oxycodone is used to relieve pain from moderate to severe. Oxycodone prolonged-release tablets and capsules are used to relieve severe pain in people who are expected to need pain medication at all times for a prolonged period and who can not be treated with other medications. Oxycodone extended-release capsules and tablets should not be used to treat pain that can be controlled with medication taken when necessary. Tablets and extended-release capsules and concentrated oxycodone solution should only be used to treat people who are tolerant (accustomed to the effects of the medication) to opioid medications, because they have taken this type of medication for at least a week . Oxycodone belongs to a class of medications called opioid analgesics (narcotics). It works by changing the way the brain and nervous system respond to pain.
Oxycodone is also available in combination with acetaminophen (Oxycet, Percocet, Roxicet, Xartemis XR, others), aspirin (Percodan) and ibuprofen. This monograph only includes information about the use of oxycodone alone. If you take a combination oxycodone product, be sure to read information about all the ingredients in the product you are taking and ask for more information from your doctor or pharmacist.
How should this medicine be used?
The presentation of oxycodone is in solution (liquid), a concentrated solution, a tablet, a capsule, a prolonged-release tablet (long-acting) (Oxycontin) and a prolonged-release capsule (Xtampza ER) to take by mouth. The solution, the concentrated solution, tablet and capsule are usually taken with or without food every 4 to 6 hours, as needed for pain or as regularly scheduled medications. Prolonged-release tablets (Oxycontin) are taken every 12 hours with or without food. The extended-release capsules (Xtampza ER) are taken every 12 hours with food; Eat the same amount of food with each dose. Carefully follow the instructions on the label of your prescription and ask your doctor or pharmacist to explain any part you do not understand. Take oxycodone exactly as directed.
If you take the Oxaydo brand tablets, swallow them one at a time with enough water. Swallow the tablet immediately after putting it in your mouth. Do not soak, wet or suck the tablets before putting them in your mouth. Do not chew or crush the Oxaydo brand tablets, nor administer them through the nasogastric tube (tube NG, a tube that is inserted through the nose to administer medications and food directly to the stomach).
If you have difficulty swallowing the extended-release capsules (Xtampza ER), you can carefully open the capsule and pour the contents into soft foods such as apple sauce, pudding, yogurt, ice cream or jam, and then consume the mixture immediately. Immediately discard the empty covers of the capsule by letting them go in the toilet. Do not store the mixture for later use.
If you have a probe for feeding, you can pour the contents of the extended-release capsules into the probe. Ask your doctor how you should take the medication and follow these instructions carefully.
If you are taking the concentrated solution, your doctor may direct you to mix the medication in a small amount of juice or semi-solid foods such as pudding or applesauce. Follow these instructions carefully. Swallow the mixture immediately; do not save it to use later.
Your doctor will probably tell you to start taking a low dose of oxycodone and increase your dose over time if your pain is not controlled. After taking oxycodone for a period of time, your body may become accustomed to the medication. If this happens, your doctor may need to increase your dose to control pain. Your doctor may lower your dose if you experience side effects. Tell your doctor how you are feeling during your treatment with oxycodone.
Do not stop taking oxycodone without talking to your doctor. If you suddenly stop taking this medication, you may experience withdrawal symptoms such as nervousness, watery eyes, runny nose, sneezing, yawning, sweating, chills, muscle or joint pains, weakness, irritability, anxiety, depression, difficulty falling asleep or remain asleep, cramps, nausea, vomiting, diarrhea, loss of appetite, rapid heart rate and rapid breathing. Your doctor will probably decrease your dose gradually.
What are the possible side effects of this medication?
Oxycodone can cause side effects. Tell your doctor if any of these symptoms are strong or do not go away:
Some Side Effects Can Be Serious. If you experience any of these symptoms or those mentioned in the IMPORTANT WARNING section, call your doctor immediately or seek emergency medical treatment:
changes in heart rhythm,
agitation, hallucinations (seeing things or hearing voices that do not exist), fever, sweating, confusion, rapid heart rate, tremors, spasms or severe muscle stiffness, loss of coordination, nausea, vomiting or diarrhea,
nausea, vomiting, lack of appetite, weakness or dizziness,
inability to achieve or maintain an erection,
less sexual desire,
inflammation of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
difficulty breathing or swallowing
Stun when you change position.
If you develop a serious side effect, you or your doctor can send a report to the Food and Drug Administration (FDA) ‘MedWatch’ adverse effects disclosure program on the website (http: // /www.fda.gov/Safety/MedWatch)
Oxycodone may cause other side effects. Call your doctor if you have any unusual problems while taking this medication